SNX13

Across TCGA cell cohorts, SNX13 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNX13-associated genes across cancer lineages are PF4V1, RLN3, and IFNB1. Each is linked with SNX13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX13-to-partner and partner-to-SNX13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PF4V1 grouped by SNX13-low versus SNX13-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX13→partner) and Y-score (partner→SNX13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PF4V1 →	+1.110	+3.536	<.001	.001	3	2
LUNG_SCLC	RLN3 →	+0.325	+3.906	<.001	.002	3	1
LUNG_SCLC	IFNB1 →	+0.061	+4.110	<.001	.001	3	1
LUNG_SCLC	ZPBP2 →	+0.087	+4.578	<.001	<.001	3	1
LUNG_SCLC	IZUMO3 →	+0.414	+3.256	<.001	.005	3	1
LUNG_SCLC	ACSM4 →	+0.039	+3.459	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

PF4V1 by SNX13 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →