SNX11

Across TCGA pan-cancer cohorts, SNX11 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNX11 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SNX11 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNX11 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, CCRCC, and UCEC are the cancer types where SNX11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	II,III,IV	0.856	0.463	.012	13	view →
CCRCC	OS	Quartile	III,IV	1.000	0.574	.014	12	view →
UCEC	OS	Median	All	1.000	0.900	.008	8	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	6	view →
PDAC	DFS	Median	IV	0.217	0.749	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNX11–LSCC (DFS)

Open the LSCC breakdown →