SNX11

Across TCGA patient cohorts, SNX11 mutation is significantly associated with the RNA expression of many other genes, with 210 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX11-associated genes across cancer lineages are LINC02719, RNU6-1245P, and CYP4F36P. Each is linked with SNX11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX11-to-partner and partner-to-SNX11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02719 grouped by SNX11-low versus SNX11-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX11→partner) and Y-score (partner→SNX11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LINC02719 →	+0.174	+5.352	<.001	.005	3	2
CESC	RNU6-1245P →	+0.341	+4.060	<.001	.004	3	2
UCEC	CYP4F36P →	+0.394	+2.620	<.001	.004	3	2
UCEC	RNU1-15P →	+0.240	+4.414	<.001	.004	3	2
UCEC	RNU4-61P →	+0.604	+3.077	<.001	<.001	3	2
SKCM	SGO1P2 →	+0.050	+4.199	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 210 associations by consensus.

LINC02719 by SNX11 expression — GBM

Explore this box plot interactively →