SNX11

Across TCGA cell cohorts, SNX11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,241 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SNX11-associated GO terms across cancer lineages are Organelle fusion, Organelle membrane fusion, and Organelle transport along microtubule. Each is linked with SNX11 in more than 10 cancer types. Because this analysis shows association rather than direction, both SNX11-to-partner and partner-to-SNX11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle fusion grouped by SNX11-low versus SNX11-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX11→partner) and Y-score (partner→SNX11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Organelle fusion →	+0.047	+0.586	.003	<.001	3	10
LUNG_SCLC	Organelle membrane fusion →	+0.056	+0.540	<.001	.001	3	10
LUNG_NSCLC_LUSC	Organelle transport along microtubule →	+0.079	+0.595	.001	.001	2	11
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.075	+0.715	<.001	.003	3	10
LUNG_SCLC	Membrane fusion →	+0.058	+0.585	<.001	<.001	2	10
STOMACH	Endosomal vesicle fusion →	+0.110	+0.778	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,241 associations by consensus.

Organelle fusion by SNX11 expression — LUNG_SCLC

Explore this box plot interactively →