SNX10

Across TCGA pan-cancer cohorts, SNX10 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNX10 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SNX10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNX10 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LSCC, GBM, and PDAC are the cancer types where SNX10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	II,III,IV	0.564	0.939	.012	18	view →
GBM	OS	Quartile	All	0.296	0.637	.010	5	view →
PDAC	DFS	Tertile	II,III,IV	0.727	0.321	.041	4	view →
LUAD	DFS	Median	All	0.606	0.887	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNX10–LSCC (DFS)

Open the LSCC breakdown →