SNX10

Across TCGA patient cohorts, SNX10 mutation is significantly associated with the RNA expression of many other genes, with 264 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX10-associated genes across cancer lineages are RNA5SP158, RN7SL722P, and RNA5SP94. Each is linked with SNX10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX10-to-partner and partner-to-SNX10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP158 grouped by SNX10-low versus SNX10-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX10→partner) and Y-score (partner→SNX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP158 →	+0.606	+5.436	<.001	.005	3	2
BRCA	RN7SL722P →	+0.119	+8.471	<.001	.005	3	1
BRCA	RNA5SP94 →	+0.276	+7.731	<.001	.009	3	1
BRCA	YWHAEP2 →	+0.269	+9.057	<.001	.003	3	1
UCEC	NDUFAF5 →	+0.541	+3.534	<.001	.002	3	1
UCEC	PITRM1 →	+0.683	+3.459	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 264 associations by consensus.

RNA5SP158 by SNX10 expression — SKCM

Explore this box plot interactively →