SNX1

Across TCGA patient cohorts, SNX1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,688 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SNX1-associated genes across cancer lineages are GINS1, GIMAP6, and CCNF. Each is linked with SNX1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SNX1-to-partner and partner-to-SNX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX1 versus GINS1 in UCEC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX1→partner) and Y-score (partner→SNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS1 →	-0.921	-0.151	<.001	.001	3	6
BRCA	GIMAP6 →	+0.864	+0.261	<.001	.001	3	6
LSCC	CCNF →	-0.645	-0.157	<.001	.003	3	6
BRCA	HPGDS →	+0.887	+0.205	<.001	<.001	3	6
GBM	IGFBP7 →	+1.021	+0.204	<.001	.001	3	6
PDAC	TMEM97 →	-0.839	-0.131	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,688 associations by consensus.

SNX1 vs GINS1 — UCEC

Explore this scatter interactively →