SNW1

Across TCGA pan-cancer cohorts, SNW1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SNW1 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNW1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SNW1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

HNSC, COAD, and LSCC are the cancer types where SNW1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	IV	0.738	0.927	.014	14	view →
COAD	DFS	Tertile	III,IV	1.000	0.793	.045	12	view →
LSCC	OS	Median	II,III,IV	0.890	0.601	.008	9	view →
PDAC	DFS	Tertile	III,IV	0.281	0.557	.013	4	view →
GBM	OS	Quartile	All	0.571	0.283	.048	2	view →
LUAD	OS	Quartile	II,III,IV	1.000	0.378	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SNW1–HNSC (OS)

Open the HNSC breakdown →