SNUPN

Across TCGA pan-cancer cohorts, SNUPN mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SNUPN data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SNUPN mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNUPN expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LUAD, HNSC, and PDAC are the cancer types where SNUPN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.344	0.805	<.001	24	view →
HNSC	OS	Tertile	III,IV	0.782	0.915	.006	17	view →
PDAC	DFS	Tertile	All	0.614	0.874	.004	15	view →
COAD	DFS	Tertile	II,III,IV	0.896	1.000	.031	12	view →
CCRCC	OS	Median	III,IV	0.104	0.989	.003	11	view →
LSCC	OS	Median	All	1.000	0.937	.012	11	view →
GBM	DFS	Median	All	0.291	0.449	.005	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SNUPN–LUAD (DFS)

Open the LUAD breakdown →