SNUPN

Across TCGA patient cohorts, SNUPN mutation is significantly associated with the RNA expression of many other genes, with 1,653 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNUPN-associated genes across cancer lineages are RNU6-241P, RNU6-210P, and BTBD10. Each is linked with SNUPN in more than 1 cancer types. Because this analysis shows association rather than direction, both SNUPN-to-partner and partner-to-SNUPN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-241P grouped by SNUPN-low versus SNUPN-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNUPN→partner) and Y-score (partner→SNUPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-241P →	+0.248	+3.662	<.001	.001	3	2
BRCA	RNU6-210P →	+0.295	+7.471	<.001	.008	3	1
UCEC	BTBD10 →	+0.533	+2.939	<.001	<.001	3	1
UCEC	LIN7C →	+0.519	+2.423	.002	.001	3	1
UCEC	PGAP2 →	+0.488	+2.818	<.001	<.001	3	1
UCEC	PTPRJ →	+0.620	+1.936	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,653 associations by consensus.

RNU6-241P by SNUPN expression — UCEC

Explore this box plot interactively →