Across TCGA patient cohorts, SNTN protein abundance is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SNTN-associated genes across cancer lineages are SPECC1, ELOF1, and CA10. Each is linked with SNTN in more than 1 cancer types. Because this analysis shows association rather than direction, both SNTN-to-partner and partner-to-SNTN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTN→partner) and Y-score (partner→SNTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SPECC1 →	+0.702	+0.672	.008	.003	3	1
LUAD	ELOF1 →	-0.647	-0.949	<.001	.007	3	1
LUAD	CA10 →	-1.761	-0.950	.002	.007	3	1
LUAD	RNU6-1093P →	-1.484	-0.822	.001	.007	3	1
LUAD	CNN2P8 →	-0.186	-0.931	.001	.009	3	1
LUAD	GRXCR1 →	-0.085	-1.156	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

SNTN survival (RNA) · tumor vs normal (RNA) · all SNTN data types