Across TCGA cell cohorts, SNTN RNA expression is significantly associated with the go_rna of many other GO terms, with 914 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SNTN-associated GO terms across cancer lineages are Adenosine metabolic process, Response to Gram-positive bacterium, and Serotonin secretion. Each is linked with SNTN in more than 4 cancer types. Because this analysis shows association rather than direction, both SNTN-to-partner and partner-to-SNTN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTN→partner) and Y-score (partner→SNTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Adenosine metabolic process →	-0.350	-0.088	<.001	.008	3	5
LUNG_NSCLC_LUAD	Response to Gram-positive bacterium →	+0.167	+0.142	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Serotonin secretion →	+0.879	+0.182	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.047	+0.124	.001	.001	3	4
LUNG_NSCLC_LUAD	Serotonin production involved in inflammatory response →	+0.879	+0.182	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Serotonin secretion involved in inflammatory response →	+0.879	+0.182	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 914 associations by consensus.

Exploration

SNTN survival (RNA) · tumor vs normal (RNA) · all SNTN data types