SNTG2

Across TCGA patient cohorts, SNTG2 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNTG2-associated genes across cancer lineages are Stathmin, ASNS, and ATM. Each is linked with SNTG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNTG2-to-partner and partner-to-SNTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Stathmin grouped by SNTG2-low versus SNTG2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTG2→partner) and Y-score (partner→SNTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Stathmin →	+0.185	+2.321	.003	.032	3	4
SKCM	ASNS →	+0.499	+2.584	.001	.009	3	3
UCEC	ATM →	-0.453	-1.584	.005	.019	3	3
UCEC	Mre11 →	+0.080	+2.936	.009	<.001	3	3
UCEC	p62 Lck ligand →	+0.354	+2.817	.002	.001	3	3
SKCM	mTOR →	-0.220	-1.584	.011	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Stathmin by SNTG2 expression — SKCM

Explore this box plot interactively →