SNTG2

Across TCGA cell cohorts, SNTG2 mutation is significantly associated with the RNA expression of many other genes, with 111 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNTG2-associated genes across cancer lineages are DUSP29, EVX2, and CCDC60. Each is linked with SNTG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNTG2-to-partner and partner-to-SNTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUSP29 grouped by SNTG2-low versus SNTG2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTG2→partner) and Y-score (partner→SNTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DUSP29 →	+0.102	+2.536	<.001	.009	3	2
BLOOD_Myeloma	EVX2 →	+0.016	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CCDC60 →	+0.033	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	MS4A10 →	+0.006	+4.867	<.001	.009	3	1
CNS	IL17A →	+0.013	+6.357	<.001	<.001	3	1
CNS	OR5J2 →	+0.073	+6.357	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 111 associations by consensus.

DUSP29 by SNTG2 expression — BLOOD_Leukemia

Explore this box plot interactively →