SNTG2

Across TCGA cell cohorts, SNTG2 mutation is significantly associated with the mutation status of many other genes, with 2,876 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNTG2-associated genes across cancer lineages are ACACB, COL4A6, and SUPT6H. Each is linked with SNTG2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SNTG2-to-partner and partner-to-SNTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACACB grouped by SNTG2-low versus SNTG2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTG2→partner) and Y-score (partner→SNTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ACACB →	+4.502	+5.066	.007	.007	1	5
LUNG_NSCLC_LUAD	COL4A6 →	+2.754	+4.189	.008	.008	1	4
BREAST	SUPT6H →	+4.297	+4.857	.009	.009	1	4
SOFT_TISSUE	SYNJ1 →	+5.502	+5.502	.003	.003	1	4
LUNG_SCLC	ASXL3 →	+2.437	+3.297	.006	.006	1	4
LARGE_INTESTINE	USP34 →	+1.404	+2.408	.006	.006	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,876 associations by consensus.

ACACB by SNTG2 expression — SOFT_TISSUE

Explore this box plot interactively →