SNTG2-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, SNTG2-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of SNTG2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where SNTG2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types SNTG2-AS1 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

UCEC, KIRC, and BRCA are the cancer types where SNTG2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNTG2-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
UCECAllAll−1.486<.0018view →
KIRCAllAll+0.596.0017view →
BRCAAllIII,IV−1.082<.0016view →
BLCAFemaleAll−0.662<.0016view →
KIRPAllIII,IV+1.276.0075view →
STADAllII,III,IV−0.413<.0015view →
LUADMaleAll−0.256.0063view →
PRADAllAll+1.075<.0012view →
KICHAllAll−0.684.0042view →
THCAMaleIII,IV−0.462<.0012view →
COADFemaleAll−0.285<.0012view →
ESCAFemaleAll−0.366<.0011view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

SNTG2-AS1–UCEC

Tumor-vs-normal expression box plot for SNTG2-AS1 RNA in UCEC.

Open the UCEC breakdown →

Exploration