SNTG1

Across TCGA patient cohorts, SNTG1 mutation is significantly associated with the total protein of many other genes, with 71 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SNTG1-associated genes across cancer lineages are Fibronectin, MYH11, and Cyclin-E2. Each is linked with SNTG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNTG1-to-partner and partner-to-SNTG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibronectin grouped by SNTG1-low versus SNTG1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTG1→partner) and Y-score (partner→SNTG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Fibronectin →	+0.387	+2.115	.022	.017	3	3
COAD	MYH11 →	-2.273	-3.313	<.001	.010	3	3
SKCM	Cyclin-E2 →	+0.150	+2.820	.049	.035	3	3
COAD	4E-BP1_pT70 →	+0.172	+2.178	.002	.035	3	3
LUAD	ERK2 →	-0.261	-1.362	.017	.035	3	2
LUAD	p90 RSK →	-0.198	-1.807	.016	.024	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

Fibronectin by SNTG1 expression — LUAD

Explore this box plot interactively →