SNTB2

Across TCGA patient cohorts, SNTB2 mutation is significantly associated with the RNA expression of many other genes, with 3,496 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNTB2-associated genes across cancer lineages are CHURC1-FNTB, MAGI2-AS2, and LINC02641. Each is linked with SNTB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNTB2-to-partner and partner-to-SNTB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHURC1-FNTB grouped by SNTB2-low versus SNTB2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTB2→partner) and Y-score (partner→SNTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHURC1-FNTB →	+0.042	+1.736	.004	.006	3	2
UCEC	MAGI2-AS2 →	+0.080	+2.833	.002	.009	3	2
UCEC	LINC02641 →	+0.144	+2.131	.006	.003	3	2
COAD	MIR6509 →	+0.482	+3.951	.008	.005	3	2
SKCM	RNA5SP282 →	+0.255	+3.490	.005	.008	3	1
SKCM	PPP1R1AP1 →	+0.141	+3.825	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,496 associations by consensus.

CHURC1-FNTB by SNTB2 expression — UCEC

Explore this box plot interactively →