SNTB2

Across TCGA cell cohorts, SNTB2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SNTB2-associated genes across cancer lineages are PF4V1, DMRTB1, and OR1L3. Each is linked with SNTB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNTB2-to-partner and partner-to-SNTB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PF4V1 grouped by SNTB2-low versus SNTB2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTB2→partner) and Y-score (partner→SNTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	PF4V1 →	+0.835	+4.432	<.001	.003	3	1
LUNG_NSCLC_LUAD	DMRTB1 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1L3 →	+0.028	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.036	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PF4V1 by SNTB2 expression — STOMACH

Explore this box plot interactively →