SNTB1

Across TCGA pan-cancer cohorts, SNTB1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SNTB1 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SNTB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNTB1 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, PDAC, and UCEC are the cancer types where SNTB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.893	.027	12	view →
PDAC	OS	Median	IV	0.491	0.836	.024	3	view →
UCEC	DFS	Quartile	All	0.921	0.737	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SNTB1–COAD (DFS)

Open the COAD breakdown →