Across TCGA pan-cancer cohorts, SNRPGP19 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SNRPGP19’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SNRPGP19 RNA is repressed in tumor relative to normal tissue. In most cancer types SNRPGP19 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.
LUSC and THCA are the cancer types where SNRPGP19 tumor–normal differential expression is most reproducible.