SNRPF

Across TCGA pan-cancer cohorts, SNRPF mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNRPF data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SNRPF mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SNRPF expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and HNSC are the cancer types where SNRPF mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.979	0.711	.009	39	view →
PDAC	DFS	Tertile	All	0.529	0.329	.005	25	view →
HNSC	DFS	Median	IV	0.554	0.772	.017	12	view →
COAD	DFS	Median	III,IV	1.000	0.846	.049	6	view →
CCRCC	OS	Median	IV	0.451	1.000	.016	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNRPF–LUAD (OS)

Open the LUAD breakdown →