SNRPD2

Across TCGA patient cohorts, SNRPD2 mutation is significantly associated with the RNA expression of many other genes, with 603 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRPD2-associated genes across cancer lineages are PTMAP3, SKA1, and CDC25A. Each is linked with SNRPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPD2-to-partner and partner-to-SNRPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTMAP3 grouped by SNRPD2-low versus SNRPD2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPD2→partner) and Y-score (partner→SNRPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PTMAP3 →	+0.370	+2.630	<.001	.006	3	2
UCEC	SKA1 →	+0.784	+3.595	.002	.001	3	2
UCEC	CDC25A →	+0.761	+3.584	.004	.003	3	2
UCEC	CDT1 →	+1.048	+3.343	<.001	.005	3	2
UCEC	RAD51 →	+0.953	+3.595	<.001	.001	3	2
UCEC	KARS1 →	+0.500	+3.595	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 603 associations by consensus.

PTMAP3 by SNRPD2 expression — SKCM

Explore this box plot interactively →