SNRPD2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNRPD2 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRPD2-associated genes across cancer lineages are Rab25, Annexin_VII, and STAT5a. Each is linked with SNRPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPD2-to-partner and partner-to-SNRPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab25 grouped by SNRPD2-low versus SNRPD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPD2→partner) and Y-score (partner→SNRPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRab25 →-0.653-3.000<.001.03631
UCECAnnexin_VII →-0.154-3.169.044.02031
UCECSTAT5a →+0.438+3.169.046.02031
UCECSTAT3_pY705 →-0.393-3.169.006.02011
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Rab25 by SNRPD2 expression — UCEC

Box plot of Rab25 in SNRPD2-low vs SNRPD2-high samples in UCEC.

Explore this box plot interactively →

Exploration