SNRPD1

Across TCGA pan-cancer cohorts, SNRPD1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNRPD1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNRPD1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SNRPD1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

HNSC, LSCC, and CCRCC are the cancer types where SNRPD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.266	1.000	.014	25	view →
LSCC	OS	Quartile	II,III,IV	1.000	0.749	.025	6	view →
CCRCC	OS	Median	All	0.902	0.984	.024	3	view →
UCEC	DFS	Median	All	0.850	0.952	.044	2	view →
PDAC	DFS	Quartile	All	0.814	0.672	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNRPD1–HNSC (OS)

Open the HNSC breakdown →