Across TCGA pan-cancer cohorts, SNRPCP20 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SNRPCP20’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where SNRPCP20 RNA is repressed in tumor relative to normal tissue. In most cancer types SNRPCP20 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA are the cancer types where SNRPCP20 tumor–normal differential expression is most reproducible.