SNRPCP11

Across TCGA pan-cancer cohorts, SNRPCP11 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SNRPCP11’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where SNRPCP11 RNA is repressed in tumor relative to normal tissue. In most cancer types SNRPCP11 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

THCA, COAD, and KIRC are the cancer types where SNRPCP11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNRPCP11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.196	.005	3	view →
COAD	Male	All	−0.226	.033	2	view →
KIRC	All	All	+0.086	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SNRPCP11–THCA

Open the THCA breakdown →