Across TCGA pan-cancer cohorts, SNRPCP10 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SNRPCP10’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SNRPCP10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNRPCP10 is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.
HNSC, BRCA, and STAD are the cancer types where SNRPCP10 tumor–normal differential expression is most reproducible.