SNRPB

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SNRPB mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SNRPB data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SNRPB mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNRPB expression acts as an unfavorable survival marker.

LSCC and HNSC are the cancer types where SNRPB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LSCCDFSTertileAll0.4370.895.00121view →
HNSCDFSMedianIII,IV0.8791.000.02011view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SNRPB–LSCC (DFS)

Kaplan–Meier survival curve for SNRPB mass-spec protein-high vs -low samples in LSCC.

Open the LSCC breakdown →

Exploration