SNRPB

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNRPB mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNRPB-associated genes across cancer lineages are Melanocytes, Endothelial cells, and mv Endothelial cells. Each is linked with SNRPB in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPB-to-partner and partner-to-SNRPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Melanocytes grouped by SNRPB-low versus SNRPB-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPB→partner) and Y-score (partner→SNRPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMelanocytes →+0.069+2.616.013.00632
SKCMEndothelial cells →-0.037-3.103.040.01931
SKCMmv Endothelial cells →-0.030-3.694.014.00131
UCECTh2 cells →+0.270+3.169.006.02011
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Melanocytes by SNRPB expression — SKCM

Box plot of Melanocytes in SNRPB-low vs SNRPB-high samples in SKCM.

Explore this box plot interactively →

Exploration