SNRPA1

Across TCGA pan-cancer cohorts, SNRPA1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SNRPA1 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SNRPA1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNRPA1 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, HNSC, and PDAC are the cancer types where SNRPA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.887	.022	24	view →
HNSC	OS	Quartile	IV	0.809	1.000	.009	8	view →
PDAC	OS	Tertile	IV	0.905	0.231	.024	5	view →
LUAD	DFS	Median	III,IV	0.432	0.925	.047	3	view →
CCRCC	OS	Median	All	0.908	0.982	.033	3	view →
GBM	DFS	Median	All	0.411	0.224	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SNRPA1–COAD (DFS)

Open the COAD breakdown →