SNRPA1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNRPA1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRPA1-associated genes across cancer lineages are CD8+ T-cells and Macrophages M1. Each is linked with SNRPA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPA1-to-partner and partner-to-SNRPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by SNRPA1-low versus SNRPA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPA1→partner) and Y-score (partner→SNRPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD8+ T-cells →+0.027+3.108<.001.01131
UCECMacrophages M1 →+0.021+2.818.023.03731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ T-cells by SNRPA1 expression — UCEC

Box plot of CD8+ T-cells in SNRPA1-low vs SNRPA1-high samples in UCEC.

Explore this box plot interactively →

Exploration