SNRPA1

Across TCGA cell cohorts, SNRPA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,825 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SNRPA1-associated GO terms across cancer lineages are DNA replication checkpoint signaling, DNA replication initiation, and Cell cycle DNA replication. Each is linked with SNRPA1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SNRPA1-to-partner and partner-to-SNRPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication checkpoint signaling grouped by SNRPA1-low versus SNRPA1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPA1→partner) and Y-score (partner→SNRPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	DNA replication checkpoint signaling →	+0.146	+1.114	.001	.009	3	18
BLOOD_Myeloma	DNA replication initiation →	+0.169	+1.001	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cell cycle DNA replication →	+0.135	+1.179	<.001	<.001	3	16
BLOOD_Myeloma	Resolution of DNA recombination intermediates →	+0.160	+0.948	.001	<.001	3	16
SOFT_TISSUE	Regulation of cell cycle checkpoint →	+0.103	+0.724	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Nuclear DNA replication →	+0.134	+1.124	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,825 associations by consensus.

DNA replication checkpoint signaling by SNRPA1 expression — LIVER

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