SNRNP70

Across TCGA pan-cancer cohorts, SNRNP70 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SNRNP70 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher SNRNP70 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNRNP70 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

MESO, LUAD, and UCEC are the cancer types where SNRNP70 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.144	0.557	.029	15	view →
LUAD	OS	Median	All	0.323	0.834	.003	12	view →
UCEC	DFS	Median	All	1.000	0.626	.014	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SNRNP70–MESO (OS)

Open the MESO breakdown →