SNRNP70

Across TCGA pan-cancer cohorts, SNRNP70 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNRNP70 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNRNP70 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNRNP70 expression acts as an unfavorable survival marker, although some lineages such as LSCC and COAD show a favorable association.

HNSC, LSCC, and COAD are the cancer types where SNRNP70 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	IV	0.597	0.887	.002	43	view →
LSCC	DFS	Quartile	II,III,IV	0.933	0.494	.009	13	view →
COAD	DFS	Median	All	1.000	0.892	.028	12	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	3	view →
PDAC	OS	Tertile	All	0.941	0.714	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNRNP70–HNSC (DFS)

Open the HNSC breakdown →