SNRNP70

Across TCGA patient cohorts, SNRNP70 mutation is significantly associated with the RNA expression of many other genes, with 1,059 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRNP70-associated genes across cancer lineages are DEFB108B, RNA5SP305, and RNU1-19P. Each is linked with SNRNP70 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRNP70-to-partner and partner-to-SNRNP70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB108B grouped by SNRNP70-low versus SNRNP70-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP70→partner) and Y-score (partner→SNRNP70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DEFB108B →	+0.282	+5.496	<.001	<.001	3	1
COAD	RNA5SP305 →	+0.562	+4.037	.005	.004	3	1
COAD	RNU1-19P →	+0.677	+4.374	.006	.002	3	1
COAD	RN7SKP76 →	+0.226	+4.962	.002	.003	3	1
COAD	RNU6-1279P →	+0.460	+4.081	<.001	.004	3	1
COAD	SNORA41B →	+0.413	+4.537	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,059 associations by consensus.

DEFB108B by SNRNP70 expression — COAD

Explore this box plot interactively →