SNRNP70

Across TCGA patient cohorts, SNRNP70 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRNP70-associated genes across cancer lineages are eEF2, FoxM1, and GAPDH. Each is linked with SNRNP70 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRNP70-to-partner and partner-to-SNRNP70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by SNRNP70-low versus SNRNP70-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP70→partner) and Y-score (partner→SNRNP70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.393	+2.321	.007	.034	3	1
UCEC	FoxM1 →	+0.275	+2.321	.010	.006	3	1
UCEC	GAPDH →	+0.484	+3.169	.028	.019	3	1
UCEC	GATA6 →	-0.237	-2.700	<.001	.005	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.358	+2.331	.042	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.183	-2.459	.008	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

eEF2 by SNRNP70 expression — UCEC

Explore this box plot interactively →