SNRNP70

Across TCGA cell cohorts, SNRNP70 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,650 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SNRNP70-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with SNRNP70 in more than 16 cancer types. Because this analysis shows association rather than direction, both SNRNP70-to-partner and partner-to-SNRNP70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by SNRNP70-low versus SNRNP70-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP70→partner) and Y-score (partner→SNRNP70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of calcium ion export across plasma membrane →	+0.085	+0.870	<.001	<.001	3	17
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.167	+1.171	<.001	<.001	3	17
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.171	+1.150	<.001	<.001	3	17
LUNG_SCLC	Constitutive heterochromatin formation →	+0.130	+0.696	<.001	.001	3	17
PANCREAS	Nucleic acid transport →	+0.088	+0.847	<.001	<.001	3	17
PANCREAS	RNA transport →	+0.088	+0.847	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,650 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by SNRNP70 expression — CNS

Explore this box plot interactively →