SNRNP70

Across TCGA cell cohorts, SNRNP70 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNRNP70-associated genes across cancer lineages are TCEAL6, GPR149, and GRIA2. Each is linked with SNRNP70 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRNP70-to-partner and partner-to-SNRNP70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCEAL6 grouped by SNRNP70-low versus SNRNP70-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP70→partner) and Y-score (partner→SNRNP70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TCEAL6 →	+0.024	+3.455	.004	.002	3	2
CNS	GPR149 →	+0.027	+5.906	<.001	<.001	3	2
LARGE_INTESTINE	GRIA2 →	+0.076	+3.629	.001	.003	3	1
LARGE_INTESTINE	TBC1D3K →	+0.262	+3.044	.001	.003	3	1
BLOOD_Leukemia	PHOX2B →	+0.022	+4.687	<.001	<.001	3	1
BLOOD_Leukemia	BRDT →	+0.137	+4.664	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

TCEAL6 by SNRNP70 expression — BLOOD_Leukemia

Explore this box plot interactively →