SNRNP48

Across TCGA pan-cancer cohorts, SNRNP48 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNRNP48 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNRNP48 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNRNP48 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, LUAD, and UCEC are the cancer types where SNRNP48 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.757	0.382	<.001	65	view →
LUAD	DFS	Median	All	0.412	0.896	.003	9	view →
UCEC	OS	Quartile	II,III,IV	1.000	0.525	.043	4	view →
GBM	DFS	Median	All	0.799	0.615	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNRNP48–HNSC (DFS)

Open the HNSC breakdown →