SNRNP48

Across TCGA patient cohorts, SNRNP48 mutation is significantly associated with the RNA expression of many other genes, with 380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRNP48-associated genes across cancer lineages are MIR4510, PSAT1P4, and LINC02380. Each is linked with SNRNP48 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNRNP48-to-partner and partner-to-SNRNP48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4510 grouped by SNRNP48-low versus SNRNP48-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP48→partner) and Y-score (partner→SNRNP48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4510 →	+0.386	+6.342	<.001	.001	3	3
UCEC	PSAT1P4 →	+0.150	+2.422	.004	.001	3	3
SKCM	LINC02380 →	+0.032	+3.555	.001	.004	3	2
COAD	PGAM3P →	+0.227	+7.142	<.001	<.001	3	2
SKCM	OR4K11P →	+0.030	+4.900	<.001	.002	3	2
SKCM	SNORD116-10 →	+0.181	+4.039	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 380 associations by consensus.

MIR4510 by SNRNP48 expression — CESC

Explore this box plot interactively →