SNRNP48

Across TCGA cell cohorts, SNRNP48 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,055 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNRNP48-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Regulation of metaphase/anaphase transition of cell cycle, and Negative regulation of cell cycle G2/M phase transition. Each is linked with SNRNP48 in more than 15 cancer types. Because this analysis shows association rather than direction, both SNRNP48-to-partner and partner-to-SNRNP48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by SNRNP48-low versus SNRNP48-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP48→partner) and Y-score (partner→SNRNP48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of double-strand break repair via homologous recombination →	+0.083	+0.833	.001	.004	3	16
BLOOD_Lymphoma	Regulation of metaphase/anaphase transition of cell cycle →	+0.110	+1.171	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle G2/M phase transition →	+0.081	+0.847	.003	.007	3	16
LARGE_INTESTINE	Microtubule organizing center organization →	+0.090	+0.963	<.001	<.001	3	16
BLOOD_Myeloma	DNA integrity checkpoint signaling →	+0.080	+0.858	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.099	+0.902	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,055 associations by consensus.

Regulation of double-strand break repair via homologous recombination by SNRNP48 expression — BLOOD_Myeloma

Explore this box plot interactively →