SNRNP48

Across TCGA cell cohorts, SNRNP48 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNRNP48-associated genes across cancer lineages are TMEM207, PRB4, and PRAMEF4. Each is linked with SNRNP48 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRNP48-to-partner and partner-to-SNRNP48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM207 grouped by SNRNP48-low versus SNRNP48-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP48→partner) and Y-score (partner→SNRNP48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMEM207 →	+0.119	+3.930	<.001	.003	3	2
LARGE_INTESTINE	PRB4 →	+0.180	+4.054	<.001	.004	3	2
LARGE_INTESTINE	PRAMEF4 →	+0.013	+4.217	<.001	.001	3	2
SOFT_TISSUE	SLC5A7 →	+0.069	+4.930	<.001	.008	3	1
SOFT_TISSUE	ZAN →	+0.006	+5.369	<.001	.004	3	1
SOFT_TISSUE	PGLYRP4 →	+0.016	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

TMEM207 by SNRNP48 expression — LARGE_INTESTINE

Explore this box plot interactively →