SNRNP40

Across TCGA pan-cancer cohorts, SNRNP40 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SNRNP40 data layer compared with 4 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SNRNP40 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNRNP40 expression acts as an unfavorable survival marker, although some lineages such as BRCA and CHOL show a favorable association.

ACC, LIHC, and LGG are the cancer types where SNRNP40 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.772	0.963	<.001	117	view →
LIHC	OS	Median	All	0.715	0.834	<.001	74	view →
LGG	DFS	Median	All	0.640	0.839	<.001	54	view →
BRCA	DFS	Quartile	III,IV	0.837	0.630	.003	43	view →
SARC	OS	Median	All	0.405	0.612	<.001	35	view →
CHOL	DFS	Median	II,III,IV	0.590	0.102	.004	31	view →
KIRC	DFS	Tertile	All	0.852	0.684	.003	30	view →
MESO	DFS	Median	IV	0.206	0.507	.003	28	view →
READ	DFS	Median	All	0.903	0.746	.001	25	view →
COAD	OS	Quartile	All	0.939	0.813	.006	19	view →
UCEC	OS	Quartile	II,III,IV	0.824	0.597	.023	18	view →
DLBC	OS	Median	All	1.000	0.759	.010	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SNRNP40–ACC (OS)

Open the ACC breakdown →