SNRNP40

Across TCGA pan-cancer cohorts, SNRNP40 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNRNP40 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNRNP40 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNRNP40 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

HNSC, LUAD, and CCRCC are the cancer types where SNRNP40 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.234	0.895	<.001	88	view →
LUAD	OS	Median	All	0.858	0.537	.003	44	view →
CCRCC	OS	Median	II,III,IV	0.485	1.000	.010	22	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.848	.025	6	view →
GBM	OS	Tertile	All	0.486	0.276	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNRNP40–HNSC (DFS)

Open the HNSC breakdown →