SNRNP27

Across TCGA pan-cancer cohorts, SNRNP27 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SNRNP27 data layer compared with 28 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SNRNP27 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNRNP27 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and GBM are the cancer types where SNRNP27 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.847	0.388	.005	17	view →
LSCC	DFS	Tertile	All	1.000	0.904	.016	15	view →
GBM	OS	Tertile	All	0.536	0.308	.022	6	view →
PDAC	OS	Median	IV	0.491	0.836	.024	3	view →
CCRCC	DFS	Median	II,III,IV	0.813	0.577	.018	2	view →
UCEC	DFS	Median	All	1.000	0.936	.023	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SNRNP27–LUAD (DFS)

Open the LUAD breakdown →