SNRNP25

Across TCGA pan-cancer cohorts, SNRNP25 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SNRNP25 data layer compared with 26 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNRNP25 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNRNP25 expression acts as an unfavorable survival marker.

HNSC and BRCA are the cancer types where SNRNP25 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.153	0.685	.009	24	view →
BRCA	OS	Median	All	0.306	0.924	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SNRNP25–HNSC (OS)

Open the HNSC breakdown →