SNRK-AS1

Across TCGA pan-cancer cohorts, SNRK-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of SNRK-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SNRK-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types SNRK-AS1 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and KIRP are the cancer types where SNRK-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNRK-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	−0.592	<.001	12	view →
THCA	Male	All	−1.225	<.001	10	view →
KIRP	Male	All	−0.649	<.001	8	view →
LUAD	All	III,IV	−0.357	<.001	8	view →
COAD	All	All	−0.285	<.001	8	view →
LIHC	All	II,III,IV	+0.103	.007	5	view →
KICH	All	All	+0.912	<.001	4	view →
BLCA	All	III,IV	−0.453	<.001	4	view →
LUSC	Male	All	−0.257	<.001	4	view →
CHOL	All	All	+1.111	<.001	2	view →
BRCA	Female	All	−0.177	.016	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

SNRK-AS1–KIRC

Open the KIRC breakdown →