Q-omics provides the consensus-scored SNORD99 profile across patient tissues and cancer cell-line models. SNORD99 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, SNORD99 is differentially expressed in 15, with the highest sampling consensus in BLCA. Additionally, SNORD99 RNA expression shows 16,444 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, BLCA, and THYM as cancer lineages where SNORD99 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNORD99 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNORD99 survival associations across molecular data types. SNORD99 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNORD99 RNA expression–survival associations across cancer types. High SNORD99 expression shows unfavorable associations in KIRC, ACC, LIHC, COAD, MESO and LGG. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for SNORD99 RNA expression.
This table summarizes SNORD99 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for SNORD99. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNORD99 shows higher tumor expression in BLCA, KIRC, COAD, STAD, HNSC and KIRP. The BLCA box plot shows higher SNORD99 RNA expression in tumor versus normal tissue (log2 FC = +2.780, t-test p < 0.001).
This table shows molecular features associated with SNORD99 in patient tissues and cancer cell lines. In patient samples, SNORD99 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
