Across TCGA pan-cancer cohorts, SNORD90 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SNORD90’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where SNORD90 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORD90 is over-expressed in tumor.

UCEC, STAD, and COAD are the cancer types where SNORD90 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD90 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.196	.020	6	view →
STAD	Female	III,IV	+1.580	.011	5	view →
COAD	Male	All	+0.213	.025	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNORD90 RNA expression & survival · all SNORD90 data types